内容摘要：Pressed against the fringes of the small northern city of Cuauhtemoc, the Mennonite settlement here spans about 40 kilometers (25 miles). With 23,000 residents, it’s one of Cuauhtemoc’s primary economic engines, but it’s an isolated place where families keep to themselves. Some have turned to social media and anti-vaccine websites for research. Others use little technology but visit family in the United States, where they also hear misinformation — which then spreads through word of mouth.

Pressed against the fringes of the small northern city of Cuauhtemoc, the Mennonite settlement here spans about 40 kilometers (25 miles). With 23,000 residents, it’s one of Cuauhtemoc’s primary economic engines, but it’s an isolated place where families keep to themselves. Some have turned to social media and anti-vaccine websites for research. Others use little technology but visit family in the United States, where they also hear misinformation — which then spreads through word of mouth.

— were short-lived. But the fifth xenotransplant recipient,as prior patients, boosted the field — thriving for now 2½ months after a pig kidney transplant at NYU Langone Health in November.

Doctors are moving from those one-off experiments to more formal studies. As they monitor Andrews’ recovery, doctors at Mass General Brigham have Food and Drug Administration permission to perform two additional transplants in their pilot study, using gene-edited pig kidneys supplied by biotech eGenesis.And United Therapeutics, another developer of gene-edited pig organs, just won FDA approval for the world’s first clinical trial of xenotransplantation. Initially, six patients will receive pig kidneys — and if they fare well over six months, up to 50 additional patients will receive transplants.“This is uncharted territory,” said Mass General’s Dr. Tatsuo Kawai, who led both Andrews’ surgery and the world’s first pig kidney transplant last year. But with lessons from animal research and the prior human attempts, he said, “I’m very optimistic. And hopefully we can get to survival, kidney survival, for over two years.”

so their organs are more humanlike to address the transplant shortage. More than 100,000 people are on the U.S. transplant list, most who need a kidney, and thousands die waiting.Andrews’ kidneys abruptly failed about two years ago, and the Concord, New Hampshire, grandfather struggled with fatigue and complications from dialysis. He’s on the transplant list but doctors warned it was a long shot. It can take seven years or more for people with Andrews’ blood type to find a matching kidney. Meanwhile, people slowly get sicker on dialysis — five-year survival is about 50% — and Andrews already had had a heart attack.

“I have seen my mortality and I was ready to fight,” Andrews said. So he asked Mass General if he could get a pig kidney instead. “I told them. ‘Anything, I’ll do anything. You give me a list of things you want me to do and I’ll do it.’”

Mass General transplant nephrologist Dr. Leonardo Riella said Andrews was weak and struggling with diabetes, including a slow-healing diabetic foot ulcer that hindered walking. He’d have to get more fit to be a candidate.Each day, hundreds of trucks carrying food and humanitarian aid would be allowed to enter Gaza, where experts say a nearly three-month Israeli blockade —

— has pushed the populationPalestinian women wait with their sick children for medical care in an overcrowded clinic in Gaza City, Wednesday, May 28, 2025. (AP Photo/Jehand Alshrafi)

Palestinian women wait with their sick children for medical care in an overcrowded clinic in Gaza City, Wednesday, May 28, 2025. (AP Photo/Jehand Alshrafi)Hamas-led militants stormed southern Israel on Oct. 7, 2023, killing some 1,200 people, mostly civilians, and abducting 251 hostages. More than half the hostages have been released in ceasefires or other deals. Israel has rescued eight and recovered dozens of bodies.