内容摘要：O’Leary said he thinks some Main Street businesses will be open sometime this summer. The council is looking for village-owned properties that can be leased or sold to business owners.

O’Leary said he thinks some Main Street businesses will be open sometime this summer. The council is looking for village-owned properties that can be leased or sold to business owners.

Marine Corps combat veteran Matt Metzger poses for a portrait with a plate of mushrooms that he grows himself for microdosing psilocybin, Wednesday, March 26, 2025, in Olympia, Wash. (AP Photo/Lindsey Wasson)These kinds of claims are hard to measure in the lab, say scientists studying microdosing.

For starters, belief is so important to the experience that empty capsules can produce the same effects.involving people who microdose, participants didn’t know until afterward whether they had spent four weeks taking their usual microdose or placebos. Psychological measures improved after four weeks for everyone in the study, regardless of whether they were taking microdoses or empty capsules.“It appears that I was indeed taking placebos throughout the trial. I’m quite astonished,” wrote one of the study participants. “It seems I was able to generate a powerful ‘altered consciousness’ experience based only (on) the expectation around the possibility of a microdose.”

Scientists haven’t found lasting effects on creativity or cognition, according to a review of a handful of small placebo-controlled trials of microdosing LSD.Matt Metzger, a Marine Corps combat veteran, displays Psilocybe cubensis mushrooms Wednesday, March 26, 2025, in Olympia, Wash. (AP Photo/Lindsey Wasson)

Matt Metzger, a Marine Corps combat veteran, displays Psilocybe cubensis mushrooms Wednesday, March 26, 2025, in Olympia, Wash. (AP Photo/Lindsey Wasson)

One small study did find glimmers of an effect of small LSD doses on vigor and elation in people with mild depression when compared with a placebo.Remarkably little of Hawaii’s 20th-century architecture has been preserved, especially in urban areas, says William Chapman, dean of the school of architecture at the University of Hawaii at Manoa.

The mid-20th-century was a particularly harsh period for historic buildings in Honolulu, he says: “We lost a lot.” What’s left is “probably two handfuls of buildings, dating back in time to the pre-territorial period, back to the 19th century.”Developers use neglect as an excuse to tear down buildings, Chapman says. “Old-timers love to talk about the house being held together because the termites hold hands, right? I get sick of that.”

This image shows an exterior view of the Manoa Heritage Center in Honolulu, founded in 1996 by Sam and Mary Cooke in 1996. (Kristina Linnea Garcia via AP)This image shows an exterior view of the Manoa Heritage Center in Honolulu, founded in 1996 by Sam and Mary Cooke in 1996. (Kristina Linnea Garcia via AP)